Multiparametric Cell Cycle Analysis by Automated Microscopy
نویسندگان
چکیده
منابع مشابه
Novel cell segmentation and online SVM for cell cycle phase identification in automated microscopy
MOTIVATION Automated identification of cell cycle phases captured via fluorescent microscopy is very important for understanding cell cycle and for drug discovery. In this article, we propose a novel cell detection method that utilizes both the intensity and shape information of the cell for better segmentation quality. In contrast to conventional off-line learning algorithms, an Online Support...
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High-content imaging is a powerful tool for determining cell phenotypes at the single cell level. Characterising the effect of small molecules on cell cycle distribution is important for understanding their mechanism of action especially in oncology drug discovery but also for understanding potential toxicology liabilities. Here, a high-throughput phenotypic assay utilising the PerkinElmer Oper...
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ژورنال
عنوان ژورنال: Journal of Biomolecular Screening
سال: 2006
ISSN: 1087-0571,1552-454X
DOI: 10.1177/1087057106289406